In the Free City of Pentos, Daenerys Targaryen lives in exile with her older brother Viserys - the son and only surviving male heir of Aerys II of house  Targaryen, who was overthrown by Robert Baratheon during the War of the Usurper.

The Targaryens had ruled Westeros as dragon-lords for about 300 years,  but their dragons and power are now gone. Viserys negotiates a marriage  contract and betroths his sister to Khal Drogo, a warlord of the nomadic Dothraki horse warriors, in exchange for use of Drogo's army to reclaim the Westeros Iron Throne for House Targaryen. The wealthy merchant, Magister Illyrio, who has been hosting Viserys and Daenerys, provides a grand send-off for the royal siblings, and a knight exiled from Westeros, Ser Jorah Mormont, joins Viserys as an advisor.

The story follows these two siblings with a sparking relationship as they travel across the Great Grass Sea and hope to emerge with an army to reclaim their rightful throne as the rulers of Westeros. Treachery and deceit lurk in the shadows to test the true power of the Blood of the Dragon.